LC (whose email handle ThrobbingSocks is much more provocative) tipped me off to this Film Threat article by Allan Heifetz which explains some of the more significant pet peeves of professional (and unprofessional) script readers.

Newbies also love to break the fourth wall. These fools must think they have super strength. “Hulk smash fourth wall! Aaargh! Hulk need to address audience for lighthearted and wacky fun! Hulk’s rom-com is effervescent and delightful! Aargh!” Unfortunately, once you have a character address the camera you are essentially saying that your movie takes place in a magical fantasy land where anyone can talk to a theatre full of people from another dimension whenever one feels the need to vent.

The full article is here.